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Lysodren 500 mg, 100 Tablets Lysodren (Mitotane) is used t ... Read more

Lysodren 500 mg, 100 Tablets Lysodren (Mitotane) is used to treat pituitary-dependent hyperadrenocorticism (Cushing's Disease) and adrenal tumors. Lysodren Miotane Prescriber Highlights - Adrenal cytoxic agent used for medical treatment of pituitary-dependent hy- peradrencorticism Caution: pregnancy, diabetes, and preexisting renal or hepatic disease Adverse Effects: Lethargy, ataxia, wekness, anorexia, vomiting, and/or diarrhea; liver changes possible. Relapses are not uncommon All dogs receiving mitotane therapy should receive additional glucocorticoid supplementation if undergoing a stress (e.g., surgery, trauma, acute illness) Monitoring is mandatorty Avoid human exposure Drug interactions Chemistry Mitotane, also commonly known in veterinary medicine as DDD, is structuarally related to the infamous insecticide, chlorophenothane (DDT). It occurs as a white, crystalline powder with slightly aromatic odor. It is practically insoluble in water and soluble in alcohol. Pharmacology While mitotane is considered an adrenal cytotoxic agent, it apparently can also inhibit adrenocortical function without causing cell destruction. the exact mechan- nisms of action for these are not clearly understood. In dogs with pituitary-dependent hyperadrenocorticism (PDH), mitotane has been dem- onstrated to cause severe, progressive necrosis of the zona fasciculata and zona reticularis . These effects occur quite rapidly (usually within 5-10 days of starting therapy). It has been stated that mitotane spares the zona glomerulosa and therefore aldosterone synthesis is un- affected. This is only partially true, as the zona glomerulosa may also be affected by mi- totane therapy, but it is uncommon for clinically significant effects on aldosterone produc- tion to be noted with therapy. Uses/Indications Inveterinary medicine, mitotane is used primarily for the medical treatment of pituitary-dependent hyperadrenocorticism (PDH), principally in the dog. It has also been used for the palliative treatment of adrenal carcinorma in humans and dogs. Contraindications/Precautions Mitotane is contraindicated in patients known to be hy- persensitive to it. Patients with concurrent diabetes mellitus may have rapidly changing insulin requirements during the initial treatment period. these animals should be closely monitored until they are clinically stable. Dogs with preexisting renal or hepatic disease should receive the drug with caution and with more intense monitoring. some clinicians recommend giving prednisolone at 0.2 mg/kg/day during the initial treatment period (0.4 mg/kg/day to diabetic dogs) to reduce the potential for side effects from acute endogenous steroid withdrawal. Other clinicians have argued that routinely administering steroids masks the clinical markers that signify when the endpoint of ther- apy has been reached and must be withdrawn 2-3 days before ACTH stimulation tests can be done. Since in adequately observed patients, adverse effects requiring glucocorticoid therapy may only be necessary in 5% of patients, the benefits of routine glucocorticoid administration may not be warranted. Dosage Dogs: For medical treatment of pituitary-dependent hyperadrenocorticism (bilateral adrenal hyperplasia): NOTE: The information provided below (in :a and b:) is a synopsis of the authors' treatment protocols. It is strongly recommended to refer to the original refer- ences and read the entire discussion before instituting therapy for the first time. a) Initiate therapy at home (preferably on a Saturday): 50 mg/kg divided twice a day, PO with food. Do not give glucocorticoids, but owner should have a small supply of prednisolone. Give until one of the f Minimize

Equi-Block DT Formula, 16 oz Equi-Block DT Formula (Daily ... Read more

Equi-Block DT Formula, 16 oz Equi-Block DT Formula (Daily Treatment) is the second stage of a three-part Pain Reduction Program. Equi-Block DT Formula (Daily Treatment) is the second stage of our three-part Pain Reduction Program. Equi-Block DT was specifically designed to treat long term chronic pain in a more cost-effective manner. It works wonders on horses suffering from debilitating diseases as well as pain stemming from old injuries. Equi-Block DT Formula is a thinner version of Racehorse Strength Equi-Block but no less potent over continued usage. As you well know by now, Capsaicin depletes Substance P. Remove the "P" and you remove the pain. Since the DT Formula is a more liquid product, it delivers lower concentrations of Capsaicin. A regular and consistent application of DT maintains the depletion of Substance P, which is necessary to drastically reduce or eliminate chronic pain altogether. We recommend Equi-Block DT Formula (Daily Treatment) for the ongoing long-term treatment of recurrent aches and pains associated with arthritis, sprains, strains, or curb and splint pain in horses. DIRECTIONS Use a liberal amount of Equi-Block DT Formula (Daily Treatment) on the effected areas twice daily (at least), never more than four. Rub in thoroughly and remove excess. If you are not sure where the affected area is, consult your Veterinarian. A good once over in the morning and again in the evening should do it. However, to insure maximum effectiveness in more serious cases, you can increase the application Equi-Block DT to three times daily. Be sure to apply to all sides of the joint when applicable. This will help your animal kick start its active periods. It will also help your animal get its proper rest. Wash your hands thoroughly after each application or wear disposable gloves to apply. Again, avoid contact with eyes and mucous membranes. Do not apply to open wounds, cuts or abrasions. CHRONIC PAIN MANAGEMENT If you have never used Equi-Block DT Formula on your animal, we suggest you start with Racehorse Strength Equi-Block for the first week, three times daily. Remember to apply to the exact areas of lameness. Then cut back to twice a day in the second week. Finally, in week three, start applying the Equi-Block DT Formula two to three times daily as recommended. You will be amazed at the results! Many people have called us with testimonials outlining the problems of their aging or severely injured horses. They describe how, using Racehorse Strength Equi-Block and Equi-Block DT Formula in combination, after three weeks their animal dramatically improved in both condition and disposition. Every time we help someone with their horse, it makes us feel that much better! RACING AND PERFORMANCE TIPS After each heavy workout, race or performance, rub your animal down with Equi-Block DT Formula. DT is a spectacular rest or sleep aid. Equi-Block DT relieves the animal of the typical aches and pains caused by over-exertion or stress. DT maintains the depletion of Substance P. Less "P" means less pain and more sleep! Be sure to use Super Strength Equi-Tite Liniment on your horse's legs. For those of you in the Snow Belt or colder regions where the temperatures dip, trainers have been using DT as a performance rub for the major muscle groups. The feed back we have been getting is that the animals seem to like the warming sensation cause by the Capsaicin. This warming sensation would normally be too hot in warmer weather conditions. However, it appears that some animals under the colder conditions respond well to the added heat. Minimize

Virbac Yard Spray Concentrate, 16 oz Yard Spray Concentrat ... Read more

Virbac Yard Spray Concentrate, 16 oz Yard Spray Concentrate is an outdoor yard treatment for fleas and ticks. VIRBAC ® YARD SPRAY CONCENTRATE Virbac Insecticidal EPA Reg. No.: 2382-122 Active Ingredient(s): Esfenvalerate: (S) -cyano (3-phenoxyphenyl) methyl-(S)-4 chloro-alpha- (1-methylethyl) benzeneacetate 0.44% Inert Ingredients 99.56%   100.00% Indications: Residual action insecticide concentrate for use outdoors on residential lawns and around residential premises only to kill fleas and ticks. Kills deer ticks and other Ixodid species that carry and transmit Lyme disease. Directions for Use: It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. To kill fleas and ticks harboring in lawns, backyards, dog kennels and runs, apply Yard Spray Concentrate through the hose end sprayer provided with this product or by compressed air sprayer or watering can. For best results, lawn should be mowed a day or two before spraying. For use with Hose End Spray Applicator: The hose end applicator cap is calibrated to deliver the correct dilution rate, and when attached to this bottle will treat 6000 square feet. To treat smaller areas, stop spraying when the appropriate amount of concentrate has been used (e.g., half the concentrate should be used for a 3000 square foot yard), reclose bottle with original cap and store bottle for next application. Separate mixing of the concentrate or other application equipment is not required. First ensure the hose faucet is turned off. Then screw end of hose into the black end of the sprayer cap. Remove bottle cap (save for closing after use). Secure sprayer cap to bottle by turning bottle counter-clockwise. Turn on faucet. Spray using a slow, even sweeping motion, being sure to cover the entire lawn surface where pets frequent. Spray under ornamentals and trees but avoid soaking young or flowering plants. Flea populations are greatest where the pet spends the most time. Therefore be sure to thoroughly soak these areas (e.g., shaded areas such as underbrushes, trees, porches, inside pet kennel and wherever your pet frequents). Repeat treatment may be necessary at 7 to 14 day intervals. For Compressed Air Sprayer or Watering Can Application: Mix two (2) fluid ounces of the concentrate per one (1) gallon of water and apply at the rate of one (1) gallon of diluted spray per 1000 square feet to surfaces of kennels, exercise runs, patios, on and under porches, crawl spaces and other outdoor areas pets frequent. Precautionary Statements: Hazards to Humans and Domestic Animals: Caution: Harmful if swallowed, absorbed through skin or inhaled, causes moderate eye irritation. Avoid breathing vapors or spray mist and contact with skin, eyes or clothing. In case of contact, flush with plenty of water. Avoid contamination of food or foodstuffs. Do not spray plants used for food or feed. Keep pets and children out of treated area until after spray has dried. Do not spray on animals. Statement of Practical Treatment: If Swallowed: Call a physician or Poison Control Center immediately. Do not induce vomiting because of aspiration pneumonia hazard. If in Eyes: Flush with plenty of water. Get immediate medical attention. If Inhaled: Remove victim to fresh air or, if not breathing, give artificial respiration, preferably mouth-to-mouth. Get medical attention. If on Skin: Wash skin with soap and warm water after use. Get medical attention if irritation persists. If on Clothing: Remove contaminated clothing and wash before re-use. Environmental Hazards: This pesticide is highly toxic to fish and aquatic invertebrates. Do not apply directly to water. Drift from treated areas may be hazardous to organisms in adjacent aquatic sites. Do not contaminate water when disposing of equipment washwaters. Storage and Disposal: Storage: Store in closed container in a cool, dry place. Disp Minimize

EicosaDerm, 32 oz EicosaDerm is the first hi-potency, conc ... Read more

EicosaDerm, 32 oz EicosaDerm is the first hi-potency, concentrated source of Omega-3 fatty acids EPA/DHA plus Vitamin E available to the veterinary market. For use in dogs and cats. EPA 360mg/DHA 240mg EicosaDerm, 32 oz. Product Description: EicosaDerm is the first hi-potency EPA (Omega-3) product available to the veterinary market. Why? Dogs & cats have strict dietary requirements for certain polyunsaturated fatty acids that are important for maintaining skin and hair coat conditions, reproductive function & tissue repair. Current research shows that Omega-3 fatty acids also play an important role in mediating and regulating inflammatory, immune & aggregatory responses within the body. Omega-3 offers considerable potential for disease prevention and in the therapeutic management of a wide variety of clinical disorders. Subsequently Omega-3 supplements have been used in veterinary trials, predominately in animals with inflammatory and immune-based conditions, with very favorable clinical responses. EicosaDerm has 16.5 calories per 2 mL. Features & Benefits Easy to use 8 oz or 32 oz liquid pump Trouble-free exact dosage One pump per 20 pounds 360 mg EPA (eicosapentaenoic acid) 240 mg DHA (docasahexaenoic acid) 10 IU - Vitamin E No sugars or starch Preservative free Excellent value Animal Weight & Recommended Daily Amount 1-10 lbs & 1/2 pump 11-20 lbs & 1 pump 21-40 lbs & 2 pumps 41-60 lbs & 3 pumps 61-80 lbs & 4 pumps Omega-3 supplements are beneficial but not limited to the following conditions: Dermatologic diseases: atopic dermatitis, food allergies, flea bite allergy, seborrhea complex, pyoderma, dry & dull coats Degenerative joint disease: hip dysplasia, pelvic arthritis Neoplasia Thromboembolic disease (dogs) Eosinophilic granuloma complex Behavioral disorders Kidney, liver, bladder and cardiac problems Minimize

This book results from requests from rabbit owners and vete ... Read more

This book results from requests from rabbit owners and veterinarians who were seeking reliable, up to date information about skin diseases and their treatment. Material related to rabbits is, indeed, not readily available, or limited to a chapter in rabbit medicine or veterinary books. Here, a comprehensive approach aims at describing a skin disorder and its rabbit-specific clinical signs, diagnosis, and rabbit-safe treatment options. The book chapters deal with rabbit skin anatomy, examination of rabbits, and viral, bacterial, fungal, parasitic, mechanical, genetic, hormonal, immune and neoplastic diseases. Pen drawings illustrate the different disorders. The collaboration with a veterinarian and a rabbit owner has contributed to the clarity and the quality of the provided information. Hopefully "Skin Diseases of Rabbits" will appeal to the small animal and exotic practitioner, veterinary students, veterinary nurses, and owners, and become a helpful addition to their handling and treating rabbits. Minimize

Felocell FIP 25 Dose Felocell FIP 25 Dose *[formerly Fel ... Read more

Felocell FIP 25 Dose Felocell FIP 25 Dose *[formerly Felocell FIP, Box of 25 Single Dose Vials] is for intranasal vaccination of healthy cats 16 weeks of age or older as an aid in preventing feline infectious peritonitis caused by feline infectious peritonitis virus (FIPV). Please Note: This product requires 1- or 2-day expedited shipping. When selecting an express service for your order, UPS 2 Day and Express Mail ship Monday-Wednesday and UPS Overnight ships Monday-Thursday. Please call if Saturday delivery is required. During summer months, purchase of 1 or 2 additional ice packs is advised. FELOCELL ® FIP Pfizer Animal Health Feline Infectious Peritonitis Vaccine Modified Live Virus For use in cats only PRODUCT DESCRIPTION: Felocell FIP is for intranasal (IN) vaccination of healthy cats 16 weeks of age or older as an aid in preventing feline infectious peritonitis caused by feline infectious peritonitis virus (FIPV). Felocell FIP contains an attenuated, temperature-sensitive (TS) strain of FIP virus propagated on an established feline cell line. The vaccine is freeze-dried to preserve stability. Cats vaccinated IN with Felocell FIP develop a protective immune response and do not become hypersensitized. This practical benefit may be attributed to the temperature-sensitive Felocell FIP vaccine strain, which replicates in the upper respiratory tract, but does not spread systemically at 39°C, the cat's body temperature. DISEASE DESCRIPTION: FIP is a complex disease of cats caused by FIPV, a coronavirus related to transmissible gastroenteritis virus (TGEV) of pigs, enteric coronavirus of dogs, and respiratory coronavirus of humans. 1 Although scientists do not completely understand its pathogenesis, they believe that FIP is an immune-mediated disease. FIPV first multiplies in epithelial cells of the upper respiratory tract and intestine. 2 Clinically apparent FIP occurs after the virus crosses the mucosal barrier and spreads throughout the cat in infected macrophages and monocytes. Primary FIP may be mild, consisting of fever and a slight nasal and ocular discharge. While most cats with the primary form of FIP recover, others become chronically infected carriers. Secondary FIP may develop following primary infection and appears in 2 forms: (1) Effusive or wet form, characterized by peritonitis and pleuritis with ascites and pleural effusion, and (2) Noneffusive or dry form, characterized by granulomatous inflammation of various organs and little or no exudate. 3,4 Both forms may appear together. Once clinical symptoms occur, FIP usually takes a fatal course. The most commonly diagnosed clinical manifestation is accumulation of fluid within the peritoneal cavity with progressive, painless enlargement of the abdomen. Infected animals also may experience difficult breathing, have an elevated temperature, appear depressed, and lose weight. Other clinical symptoms, such as ocular involvement, disseminated intravascular coagulation, and renal involvement, are observed occasionally. 5 Exudate obtained from body cavities by paracentesis appears pale yellow or golden in color and is relatively clear. Hemograms of cats with FIP typically indicate a stress response. There may be a mild to moderate anemia and leukocytosis attributed to an increased percentage of neutrophils. FIP most frequently occurs in young cats between the ages of 6 months and 2 years of age. Incidence of disease is also higher in older cats, between 11 and 15 years of age. SAFETY AND EFFICACY: Comprehensive tests were conducted to demonstrate the safety of Felocell FIP. In these tests, Felocell FIP did not cause illness in cats when administered intranasally. It did not cause illness in cats infected with feline leukemia, in cats exposed to feline enteric coronavirus, in dexamethasone-immunosuppressed cats, in nonvaccinated cats that survived FIP challenge, or in kittens. Felocell FIP did not interfere with the developmen Minimize

Trifexis for Dogs 60.1-120 lbs, 6 Chewable Tablets (Brown) ... Read more

Trifexis for Dogs 60.1-120 lbs, 6 Chewable Tablets (Brown) Trifexis for Dogs 60.1-120 lbs, 6 Chewable Tablets (Brown) offers 3-way protection for dogs against fleas, heartworm, and intestinal worms in a flavored, chewable tablet. Trifexis pet meds kill fleas, prevent further infestations and heartworm disease, and also controls hookworm, whipworm, and roundworm. TRIFEXIS™ Elanco (spinosad + milbemycin oxime) Chewable Tablets Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Description: TRIFEXIS (spinosad and milbemycin oxime) is available in five sizes for oral administration to dogs and puppies according to their weight. Each chewable flavored tablet is formulated to provide a minimum spinosad dose of 13.5 mg/lb (30 mg/kg) and a minimum milbemycin oxime dose of 0.2 mg/lb (0.5 mg/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa . Spinosyn A and spinosyn D have the chemical compositions C 41 H 65 NO 10 and C 42 H 67 NO 10 , respectively. Milbemycin oxime is a macrocyclic lactone anthelmintic, containing two major factors, A 3 and A 4 of milbemycin oxime. The approximate ratio of A 3 :A 4 is 20:80. Milbemycin A 4 5-oxime has the chemical composition of C 32 H 45 NO 7 and milbemycin A 3 5-oxime has the chemical composition of C 31 H 43 NO 7 . Indications: TRIFEXIS is indicated for the prevention of heartworm disease (Dirofilaria immitis) . TRIFEXIS kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis) , and the treatment and control of adult hookworm (Ancylostoma caninum) , adult roundworm (Toxocara canis and Toxascaris leonina) and adult whipworm (Trichuris vulpis) infections in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater. Dosage and Administration: TRIFEXIS is given orally, once a month at the minimum dosage of 13.5 mg/lb (30 mg/kg) spinosad and 0.2 mg/lb (0.5 mg/kg) milbemycin oxime body weight. For heartworm prevention, give once monthly for at least 3 months after exposure to mosquitoes (see EFFECTIVENESS ). Dosage Schedule: Body Weight Spinosad Per Tablet (mg) Milbemycin oxime Per Tablet (mg) Tablets Administered 5 to 10 lbs 140 2.3 One 10.1 to 20 lbs 270 4.5 One 20.1 to 40 lbs 560 9.3 One 40.1 to 60 lbs 810 13.5 One 60.1 to 120 lbs 1620 27 One Over 120 lbs Administer the appropriate combination of tablets Administer TRIFEXIS with food for maximum effectiveness. If a dose is missed and a monthly interval between doses is exceeded, then immediate administration of TRIFEXIS with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations. If vomiting occurs within an hour of administration, redose with another full dose. Heartworm Prevention: TRIFEXIS should be administered at monthly intervals beginning within 1 month of the dog's first seasonal exposure and continuing until at least 3 months after the dog's last seasonal exposure to mosquitoes (see EFFECTIVENESS ). TRIFEXIS may be administered year round without interruption. When replacing another heartworm preventative product, the first dose of TRIFEXIS should be given within a month of the last dose of the former medication. Flea Treatment and Prevention: Treatment with TRIFEXIS may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatme Minimize

Trifexis for Dogs 5-10 lbs, 6 Chewable Tablets (Pink) Trif ... Read more

Trifexis for Dogs 5-10 lbs, 6 Chewable Tablets (Pink) Trifexis for Dogs 5-10 lbs, 6 Chewable Tablets (Pink) are chewable heartworm and flea control tablets for dogs and puppies 8 weeks of age or older. Trifexis prevents and controls flea infestations, controls hookworm, roundworm, whipworm, and protects against heartworm disease. TRIFEXIS™ Elanco (spinosad + milbemycin oxime) Chewable Tablets Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Description: TRIFEXIS (spinosad and milbemycin oxime) is available in five sizes for oral administration to dogs and puppies according to their weight. Each chewable flavored tablet is formulated to provide a minimum spinosad dose of 13.5 mg/lb (30 mg/kg) and a minimum milbemycin oxime dose of 0.2 mg/lb (0.5 mg/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa . Spinosyn A and spinosyn D have the chemical compositions C 41 H 65 NO 10 and C 42 H 67 NO 10 , respectively. Milbemycin oxime is a macrocyclic lactone anthelmintic, containing two major factors, A 3 and A 4 of milbemycin oxime. The approximate ratio of A 3 :A 4 is 20:80. Milbemycin A 4 5-oxime has the chemical composition of C 32 H 45 NO 7 and milbemycin A 3 5-oxime has the chemical composition of C 31 H 43 NO 7 . Indications: TRIFEXIS is indicated for the prevention of heartworm disease (Dirofilaria immitis) . TRIFEXIS kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis) , and the treatment and control of adult hookworm (Ancylostoma caninum) , adult roundworm (Toxocara canis and Toxascaris leonina) and adult whipworm (Trichuris vulpis) infections in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater. Dosage and Administration: TRIFEXIS is given orally, once a month at the minimum dosage of 13.5 mg/lb (30 mg/kg) spinosad and 0.2 mg/lb (0.5 mg/kg) milbemycin oxime body weight. For heartworm prevention, give once monthly for at least 3 months after exposure to mosquitoes (see EFFECTIVENESS ). Dosage Schedule: Body Weight Spinosad Per Tablet (mg) Milbemycin oxime Per Tablet (mg) Tablets Administered 5 to 10 lbs 140 2.3 One 10.1 to 20 lbs 270 4.5 One 20.1 to 40 lbs 560 9.3 One 40.1 to 60 lbs 810 13.5 One 60.1 to 120 lbs 1620 27 One Over 120 lbs Administer the appropriate combination of tablets Administer TRIFEXIS with food for maximum effectiveness. If a dose is missed and a monthly interval between doses is exceeded, then immediate administration of TRIFEXIS with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations. If vomiting occurs within an hour of administration, redose with another full dose. Heartworm Prevention: TRIFEXIS should be administered at monthly intervals beginning within 1 month of the dog's first seasonal exposure and continuing until at least 3 months after the dog's last seasonal exposure to mosquitoes (see EFFECTIVENESS ). TRIFEXIS may be administered year round without interruption. When replacing another heartworm preventative product, the first dose of TRIFEXIS should be given within a month of the last dose of the former medication. Flea Treatment and Prevention: Treatment with TRIFEXIS may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with TRIFEXIS should continue Minimize

Trifexis for Dogs 20.1-40 lbs, 6 Chewable Tablets (Green) ... Read more

Trifexis for Dogs 20.1-40 lbs, 6 Chewable Tablets (Green) Trifexis for Dogs 20.1-40 lbs, 6 Chewable Tablets (Green) is a once-monthly oral pet medication that protects dogs from fleas, heartworms, and intestinal parasites. Trifexis for dogs protects against heartworm disease, flea infestations, and kills existing fleas. TRIFEXIS™ Elanco (spinosad + milbemycin oxime) Chewable Tablets Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Description: TRIFEXIS (spinosad and milbemycin oxime) is available in five sizes for oral administration to dogs and puppies according to their weight. Each chewable flavored tablet is formulated to provide a minimum spinosad dose of 13.5 mg/lb (30 mg/kg) and a minimum milbemycin oxime dose of 0.2 mg/lb (0.5 mg/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa . Spinosyn A and spinosyn D have the chemical compositions C 41 H 65 NO 10 and C 42 H 67 NO 10 , respectively. Milbemycin oxime is a macrocyclic lactone anthelmintic, containing two major factors, A 3 and A 4 of milbemycin oxime. The approximate ratio of A 3 :A 4 is 20:80. Milbemycin A 4 5-oxime has the chemical composition of C 32 H 45 NO 7 and milbemycin A 3 5-oxime has the chemical composition of C 31 H 43 NO 7 . Indications: TRIFEXIS is indicated for the prevention of heartworm disease (Dirofilaria immitis) . TRIFEXIS kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis) , and the treatment and control of adult hookworm (Ancylostoma caninum) , adult roundworm (Toxocara canis and Toxascaris leonina) and adult whipworm (Trichuris vulpis) infections in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater. Dosage and Administration: TRIFEXIS is given orally, once a month at the minimum dosage of 13.5 mg/lb (30 mg/kg) spinosad and 0.2 mg/lb (0.5 mg/kg) milbemycin oxime body weight. For heartworm prevention, give once monthly for at least 3 months after exposure to mosquitoes (see EFFECTIVENESS ). Dosage Schedule: Body Weight Spinosad Per Tablet (mg) Milbemycin oxime Per Tablet (mg) Tablets Administered 5 to 10 lbs 140 2.3 One 10.1 to 20 lbs 270 4.5 One 20.1 to 40 lbs 560 9.3 One 40.1 to 60 lbs 810 13.5 One 60.1 to 120 lbs 1620 27 One Over 120 lbs Administer the appropriate combination of tablets Administer TRIFEXIS with food for maximum effectiveness. If a dose is missed and a monthly interval between doses is exceeded, then immediate administration of TRIFEXIS with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations. If vomiting occurs within an hour of administration, redose with another full dose. Heartworm Prevention: TRIFEXIS should be administered at monthly intervals beginning within 1 month of the dog's first seasonal exposure and continuing until at least 3 months after the dog's last seasonal exposure to mosquitoes (see EFFECTIVENESS ). TRIFEXIS may be administered year round without interruption. When replacing another heartworm preventative product, the first dose of TRIFEXIS should be given within a month of the last dose of the former medication. Flea Treatment and Prevention: Treatment with TRIFEXIS may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with TRIFEXIS should continue the entire Minimize

Esbilac Milk Replacer, 28 oz Powder Recommended as a food ... Read more

Esbilac Milk Replacer, 28 oz Powder Recommended as a food source for orphaned or rejected puppies or those nursing but needing supplemental feeding. ESBILAC ® POWDER PetAg Puppy Milk Replacer Food supplement for dogs For puppies newborn to 6 weeks of age #1 Selling Brand All natural with vitamins, minerals and trace nutrients Directions for Mixing Esbilac ® Powder Gently stir or shake 1 part powdered Esbilac into 2 parts warm water (a part may be a teaspoon, tablespoon or cup). Do not mix more Esbilac than can be consumed in 24 hours. Do not use a blender. Reconstituted Esbilac should be kept refrigerated. One 12 oz (340g) can of powder makes approximately 60 oz (1800ml) of liquid mixed 1:2. One 28 oz (794g) can of powder makes approximately 140 oz (4140ml) of liquid mixed 1:2. Directions for Feeding All puppies should receive their mother’s milk for at least 2 days, if possible. This colostrum milk gives extra nutrition and temporary immunity against some diseases. Warm reconstituted Esbilac to room or body temperature before serving. Feed puppies 2 tablespoons (30ml) of liquid Esbilac per 4 ounces (115g) of body weight daily. The daily feeding amount should be divided into equal portions for each feeding. Puppies’ needs will vary and this amount may have to be increased or decreased depending on the individual. Young and/or weak puppies should be fed every 3 to 4 hours. Older puppies can do well being fed every 8 hours. Weigh the puppies 3 times per week to assure adequate feeding. Consult your veterinarian for additional advice. The PetAg 2 oz (60ml) or 4 oz (120ml) Small Animal Nurser is suited for feeding most puppies. When puppies are old enough to lap, begin offering reconstituted Esbilac in a saucer. During the 5th week mix reconstituted Esbilac with Esbilac ® 2nd Step™ Puppy Weaning Food. Use of the Esbilac and 2nd Step will allow the puppy to be gradually switched to solid food. Pregnant and lactating females: Feed 2 teaspoons (4g) Esbilac powder per 5 lbs. (2.2kg) body weight daily. Growing puppies already on solid food, show dogs, and/or convalescing dogs: Feed 1 teaspoon (2g) Esbilac powder per 5 lbs. (2.2kg) body weight daily by top dressing food. Storage Reconstituted Esbilac must be kept refrigerated for up to 24 hours. Opened powder must be refrigerated for up to 3 months, or can be frozen for up to 6 months to preserve freshness. Ingredients Vegetable oil, dried skimmed milk, casein, cream, DL-methionine, L-arginine, calcium carbonate, choline chloride, lecithin, magnesium sulfate, potassium chloride, monopotassium phosphate, salt, tricalcium phosphate, carrageenan, dipotassium phosphate, taurine, ascorbic acid, ferrous sulfate, zinc sulfate, vitamin A supplement, vitamin E supplement, niacin supplement, calcium pantothenate, copper sulfate, thiamine hydrochloride, pyridoxine hydrochloride, riboflavin, manganese sulfate, vitamin D3 supplement, potassium citrate, potassium iodide, folic acid, vitamin B12 supplement, menadione sodium bisulfite complex, biotin. Guaranteed Analysis Crude Protein, min 33.0% Crude Fat, min 40.0% Crude Fiber, max 0.0% Moisture, max 5.0% Calorie Content (Calculated) The calorie content (ME) is 900 kcal/kg or 13.5kcal/tbs when powder is reconstituted 1:2. Not for human consumption. All states have laws governing the care of wildlife, and there are a number of potential health hazards that may exist. We have available a list of wildlife professionals nationwide. Call a member of the NWRA, or our toll free number for assistance. 2009 PetAg, Inc., 255 Keyes Avenue, Hampshire, IL 60140 U.S.A. 1-800-323-0877 Visit our website: www.petag.com Made in U.S.A. International Copyright Reserved. Use before date stamped on top or bottom. Sold by weight not by volume NET WT.   12 x 12 OZ. (340g) Minimize

There is currently a lot of interest within veterinary medi ... Read more

There is currently a lot of interest within veterinary medicine in both dermatology and exotics, yet, despite this interest, there is no single text available that focuses on both these key areas.This book, for the first time, provides a practical guide to dermatological problems in birds, reptiles, fish and mammals. Divided into the four groups, each section has a chapter introducing the structure and function of the skin of each group, a chapter on examination and diagnostic tests, and further chapters on species specific skin diseases and treatments.Written in a quick reference format and including almost 200 colour photographs, this book is a handy resource for veterinary practitioners, veterinary students and veterinary dermatologists alike. Minimize

Felocell 4, 25 Single Dose Vials A modified live virus vac ... Read more

Felocell 4, 25 Single Dose Vials A modified live virus vaccine for the protection of cats against Feline Panleukopenia, Rhinotracheitis, Calici Viruses and Chlamydia. Please Note: This product requires 1- or 2-day expedited shipping. When selecting an express service for your order, UPS 2 Day and Express Mail ship Monday-Wednesday and UPS Overnight ships Monday-Thursday. Please call if Saturday delivery is required. During summer months, purchase of 1 or 2 additional ice packs is advised. FELOCELL ® 4 Pfizer Animal Health Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Vaccine Modified Live Virus and Chlamydia For use in cats only PRODUCT DESCRIPTION: Fellocell 4 is for vaccination of healthy cats as an aid in preventing feline viral rhinotracheitis (FVR) caused by feline herpesvirus-1, feline respiratory disease caused by feline calicivirus (FCV), feline panleukopenia caused by feline parvovirus (FPV), and feline chlamydiosis caused by Chlamydia psittaci . Fellocell 4 contains attenuated strains of feline rhinotracheitis virus, calicivirus, and panleukopenia virus (Johnson Snow Leopard strain), and C. psittaci, propagated on established cell lines. Fellocell 4 is packaged in freeze-dried form with inert gas in place of vacuum. SAFETY AND EFFICACY: Safety of Fellocell 4 was demonstrated in field trials involving 2,288 cats. The majority of cats exhibited no serious postvaccination reactions attributable to the vaccine. However, approximately 1% of vaccinated cats exhibited lethargy, anorexia, and fever after vaccination. (See PRECAUTION 7.) Efficacy of Fellocell 4 was determined by challenge-of-immunity tests. Vaccinated cats experienced significantly less severe clinical signs than nonvaccinated control cats after challenge with virulent FVR virus, FCV, FPV, or C. psittaci . Results of serological studies indicated that no immunologic interference existed among the vaccine fractions. In specific-pathogen-free cats, vaccination with Fellocell 4 stimulated serologic titers to each of the 4 vaccine fractions. DURATION OF SEROLOGIC RESPONSE: In cats vaccinated and boostered as kittens, and then vaccinated again approximately 1 year later, revaccination with Felocell 4 has been demonstrated (under field conditions) to result in serum antibody titers that persist for 12-36 months against FPV (hemagglutination inhibition [HAI] titer > 1:40), FCV (serum neutralization [SN] titer > 1:32) and FHV (SN > 1:16). Protection against infectious agents involves a complex interplay between humoral immunity, cellular immunity, or a combination of both. The purpose of vaccination is to induce effector cells in both these arms of the immune system. During the process, long-term immunity in the form of memory T and B lymphocytes is produced. Memory cells and antibodies interact to provide protection to an animal challenged with the same pathogen at a later date. Depending on the vaccine and the disease, antibodies may be produced that provide complete protection from disease and prevent or reduce shedding. In other cases, antibodies may play a minor or ineffective role and protection from disease relies on systemic, local cellular immunity and/or local antibody production. The role of sustained serological titers in the prevention of disease has not been confirmed. In companion animals, immunological response to infection or vaccination has generally been evaluated by measuring the level of antibodies in serum and correlating these with protection or susceptibility. For certain diseases, such as feline panleukopenia, evaluation of antibody titers can be a valuable diagnostic indicator to determine when revaccination may be needed. 1,2 For other diseases, a serological response has not been identified that correlates with protection. Practical knowledge of the disease, the vaccine and the patient, along with serologic test results when appropriate, is paramount in making the best recommendat Minimize

Ecto-Soothe 3X Shampoo, 16 oz Kills fleas as it soothes th ... Read more

Ecto-Soothe 3X Shampoo, 16 oz Kills fleas as it soothes the irritated pruritic skin commonly associated with external parasites. For use on dogs, cats, puppies, and kittens 12 weeks of age and older. ECTO-SOOTHE™ 3X SHAMPOO Virbac EPA Reg. No.: 2382-117 Active Ingredient(s): Pyrethrins 0.15% Piperonyl butoxide technical* 1.50% N-octyl bicycloheptene dicarboximide 0.50% Inert ingredients 97.85% Total 100.00% *Equivalent to 1.2% (butylcarbityl) (6-propylpiperonyl) ether and 0.3% related compounds. Indications: Kills ticks, fleas and lice on dogs, cats, puppies and kittens. Directions for Use: It is a violation of federal law to use the product in a manner inconsistent with its labeling. Application: Shake well before using. Wet the animal thoroughly with warm water. Apply the product to the back of the animal and massage well into the skin to obtain a good lathering of the entire body. Allow the lather to remain in contact with the skin for at least 10 minutes. Rinse the animal thoroughly with warm water. For maximum results, repeat the process as directed above. Dry the animal thoroughly and comb. Repeat shampoo as indicated. Precautionary Statements: Hazards to Humans and Domestic Animals: Harmful if swallowed. Avoid contact with eyes and mouth of animal. Do not treat puppies or kittens under six weeks of age. Avoid contamination of feed, foodstuffs, or food handling equipment. Wash thoroughly with soap and water after using. Statement of Practical Treatment: In case of contact, immediately flush eyes with plenty of water and get medical treatment if irritation persists. Environmental Hazards: The pesticide is toxic to aquatic organisms. Do not apply directly to water. Do not contaminate water by the cleaning of equipment or the disposal of wastes. Storage and Disposal: Storage: Store in a closed container in a cool, dry area. Disposal: Do not re-use the empty container. Wrap the container in newspaper and put it in the trash. Warning(s): Keep out of the reach of children. Presentation: Available in 8 fl oz (237 mL), 16 fl oz (474 mL) and 1 gallon (3.78 L) containers. NAC No.: 10230240 Minimize

Strongid T, Quart For the removal and control of mature in ... Read more

Strongid T, Quart For the removal and control of mature infections of large strongyles, pinworms, large roundworms, and small strongyles in horses and ponies. STRONGID ® T Pfizer Animal Health (pyrantel pamoate) Equine Anthelmintic Suspension Strongid T is a suspension of pyrantel pamoate in a palatable caramel-flavored vehicle. Each mL contains 50 mg of pyrantel base as pyrantel pamoate. Pyrantel pamoate is a compound belonging to a family classified chemically as tetrahydropyrimidines. It is a yellow, water-insoluble crystalline salt of the tetrahydropyrimidine base and pamoic acid containing 34.7% base activity. ( E )-1,4,5,6-Tetrahydro-1-methyl-2-[2-(2-thienyl) vinyl] pyrimidine 4,4' methylenebis [3- hydroxy-2-naphthoate] (1:1) INDICATIONS FOR USE: For the removal and control of mature infections of large strongyles (Strongylus vulgaris, S. edentatus, S. equinus); pinworms (Oxyuris equi); large roundworms (Parascaris equorum); and small strongyles in horses and ponies. DOSAGE AND TREATMENT: Administer 3 mg pyrantel base per lb of body weight (6 mL Strongid T per 100 lb of body weight). For maximum control of parasitism, it is recommended that foals (2-8 months of age) be dosed every 4 weeks. To minimize potential hazard that the mare may pose to the foal, she should be treated 1 month prior to anticipated foaling date followed by retreatment 10 days to 2 weeks after birth of foal. Horses over 8 months of age should be routinely dosed every 6 weeks. DIRECTIONS FOR USE: Strongid T may be administered by means of a stomach tube, dose syringe or by mixing into the feed. Stomach Tube: Measure the appropriate dosage of Strongid T and mix in the desired quantity of water. Protect drench from direct sunlight and administer to the animal immediately following mixing. Do not attempt to store diluted suspension. Strongid T is inactive against the common horse bot (Gasterophilus sp.). However, Strongid T may be administered concurrently with carbon disulfide observing the usual precautions with carbon disulfide. Dose Syringe: Draw the appropriate dosage of Strongid T into a dose syringe and administer to the animal. Do not expose Strongid T to direct sunlight. Feed: Mix the appropriate dosage of Strongid T in the normal grain ration. Fasting of animals prior to or following treatment is not required. CAUTION: THIS PRODUCT IS A SUSPENSION AND AS SUCH WILL SEPARATE. TO INSURE UNIFORM RESUSPENSION AND TO ACHIEVE PROPER DOSAGE, IT IS EXTREMELY IMPORTANT THAT THE PRODUCT BE SHAKEN AND STIRRED THOROUGHLY BEFORE EVERY USE. EFFICACY: Critical (worm-count) studies in horses demonstrated that Strongid T administered at the recommended dosage was efficacious against mature infections of Strongylus vulgaris (>90%), S. edentatus (69%), S. equinus (>90%), Oxyuris equi (81%), Parascaris equorum (>90%), and small strongyles (>90%). SAFETY: Strongid T is well tolerated by horses and ponies of all ages. No adverse drug response was observed when dose rates up to 60 mg pyrantel base per lb of body weight were administered by stomach tube nor when 3 mg base per lb was given by intratracheal injection. The reproductive performance of pregnant mares and stud horses dosed with Strongid T has not been affected.   WARNINGS: Not for horses or ponies intended for food. Keep out of the reach of children.   CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. It is recommended that severely debilitated animals not be treated with this preparation. RECOMMENDED STORAGE: Store below 30°C (86°F). NADA #91-739, Approved by FDA Distributed by: Pfizer Animal Health, Exton, PA 19341, USA, Div. of Pfizer Inc, NY, NY 10017 004 75-7972-00 Net Contents:   1 quart (946 mL) 85-7972-00 NAC No.: 36901432 Minimize

SnugglePuppie, Brown Mutt Designed to help the young anima ... Read more

SnugglePuppie, Brown Mutt Designed to help the young animals adjust to their new homes, the SnugglePuppies and SnuggleKitties are great for all ages and species. They help alleviate separation anxiety, loneliness, and stress. SnugglePuppie, Brown Mut Product Description: SnugglePuppies®, with a new and improved heartbeat, are sure to capture you and your pet's heart! All ages of animals use our adorable SnugglePuppie® because they connect with the real feel heartbeat and gentle warmth. Remember that children and seniors love to cuddle them too! Heartbeat with batteries and two types of heat included. Machine washable, gentle cycle and mild detergent - nothing small to chew off either, as safety and security are our utmost concern. This product was designed to help calm, soothe and allow pets (and their people!) to sleep better. Who use's a SnugglePuppie® or SnuggleKittie® Really, just about anyone!   Animal caregivers like Vets, foster parents, breeders, people adopting pets, kennel owners and animal control officers. Wild animal rehabilitators and zookeepers.; people with singletons (when one puppy is born) or orphans or a SnugglePuppie® or SnuggleKittie® can be used when one pet dies in the family. Will my dog eat the SnugglePuppie® We always suggest supervision when you start using a SnugglePuppie® (cats don't have this problem, although they do suckle, which is okay) and use it for bedtime. If you have a known chewer, don't use the SnugglePuppie® during play time and please do not play tug with a SnugglePuppie®. But if you are giving a SnugglePuppie® during a stressful moment (crying, lost mate, travel, etc) then the SnugglePuppie® will act like a sleeping littermate and calm your puppy. We also made sure there is nothing small to chew off (just in case)! How do SnugglePuppies® or SnuggleKitties® work? They have an underside pouch where you insert the heartbeat (watch or calculator style batteries are included) and heater. There is a separate inner pocket for the baby bottle located in the underside pouch. The heaters are all natural and safe. The stuffed animal is machine washable - don’t forget to remove the contents when washing. What are SnugglePuppies® or SnuggleKitties® for? Designed to help the young animals adjust to their new homes, the SnugglePuppies® and SnuggleKitties ® are great for all ages and species. They help alleviate separation anxiety, loneliness, and stress. Great for people who travel (with or without their pets); great for people who crate train; great for trips to the Vet; great for orphaned animals (they have been called a "Virtual Mom" for good reason!); great for people who can not have animals. Microwave Instructions DO NOT place the SnugglePUPPie® OR SnuggleKittie® in the microwave. You DO NOT place the heat bags in the microwave either (they will spark).You DO place the terry cloth pouch with your dry rice in the microwave. Again, please follow our directions that come with your SnugglePuppie® or SnuggleKittie®. What is a SnugglePuppie® or SnuggleKittie® They are the original and award-winning plush stuffed animals with a heartbeat, heaters and place for a baby bottle. They come with battery-operated heartbeat and two forms of soothing, comfortable heat. Beating Heartbeat To use the heart, first remove the white tab from the heart and discard, then simply switch on. Replace the batteries with a quality brand when necessary, using 2 of stye 357 or 3 of style 389 calculator or watch batteries. Place heart in the underside pocket. Why do animals love them? Because, we believe, that animals have feelings too. Animals cry during separation anxiety, they whimper when feeling lonely, they even show stress. A SnugglePuppie® or SnuggleKittie® acts like a sleeping littermate and works to end the cryin Minimize

SnugglePuppie, Boxer/Bulldog Designed to help the young an ... Read more

SnugglePuppie, Boxer/Bulldog Designed to help the young animals adjust to their new homes, the SnugglePuppies and SnuggleKitties are great for all ages and species. They help alleviate separation anxiety, loneliness, and stress. SnugglePuppy, Boxer / Bull Dog Product Description: SnugglePuppies®, with a new and improved heartbeat, are sure to capture you and your pet's heart! All ages of animals use our adorable SnugglePuppie® because they connect with the real feel heartbeat and gentle warmth. Remember that children and seniors love to cuddle them too! Heartbeat with batteries and two types of heat included. Machine washable, gentle cycle and mild detergent - nothing small to chew off either, as safety and security are our utmost concern. This product was designed to help calm, soothe and allow pets (and their people!) to sleep better. Who use's a SnugglePuppie® or SnuggleKittie® Really, just about anyone!   Animal caregivers like Vets, foster parents, breeders, people adopting pets, kennel owners and animal control officers. Wild animal rehabilitators and zookeepers.; people with singletons (when one puppy is born) or orphans or a SnugglePuppie® or SnuggleKittie® can be used when one pet dies in the family. Will my dog eat the SnugglePuppie® We always suggest supervision when you start using a SnugglePuppie® (cats don't have this problem, although they do suckle, which is okay) and use it for bedtime. If you have a known chewer, don't use the SnugglePuppie® during play time and please do not play tug with a SnugglePuppie®. But if you are giving a SnugglePuppie® during a stressful moment (crying, lost mate, travel, etc) then the SnugglePuppie® will act like a sleeping littermate and calm your puppy. We also made sure there is nothing small to chew off (just in case)! How do SnugglePuppies® or SnuggleKitties® work? They have an underside pouch where you insert the heartbeat (watch or calculator style batteries are included) and heater. There is a separate inner pocket for the baby bottle located in the underside pouch. The heaters are all natural and safe. The stuffed animal is machine washable - don’t forget to remove the contents when washing. What are SnugglePuppies® or SnuggleKitties® for? Designed to help the young animals adjust to their new homes, the SnugglePuppies® and SnuggleKitties ® are great for all ages and species. They help alleviate separation anxiety, loneliness, and stress. Great for people who travel (with or without their pets); great for people who crate train; great for trips to the Vet; great for orphaned animals (they have been called a "Virtual Mom" for good reason!); great for people who can not have animals. Microwave Instructions DO NOT place the SnugglePUPPie® OR SnuggleKittie® in the microwave. You DO NOT place the heat bags in the microwave either (they will spark).You DO place the terry cloth pouch with your dry rice in the microwave. Again, please follow our directions that come with your SnugglePuppie® or SnuggleKittie®. What is a SnugglePuppie® or SnuggleKittie® They are the original and award-winning plush stuffed animals with a heartbeat, heaters and place for a baby bottle. They come with battery-operated heartbeat and two forms of soothing, comfortable heat. Beating Heartbeat To use the heart, first remove the white tab from the heart and discard, then simply switch on. Replace the batteries with a quality brand when necessary, using 2 of stye 357 or 3 of style 389 calculator or watch batteries. Place heart in the underside pocket. Why do animals love them? Because, we believe, that animals have feelings too. Animals cry during separation anxiety, they whimper when feeling lonely, they even show stress. A SnugglePuppie® or SnuggleKittie® acts like a sleeping littermate and works to en Minimize

Renal Advanced Powder Kidney Support for Dogs, 80 gm Renal ... Read more

Renal Advanced Powder Kidney Support for Dogs, 80 gm Renal Advanced Powder Kidney Support for Dogs, 80 gm is a nutritional supplement that aids dogs with kidney disease by preventing hypokalemia, replenishing the loss of B Vitamins, controlling metabolic acidosis and helping to reduce azotemia. Renal Advanced Powder Kidney Support For Dogs B-Vitamin Kidney Supplements for Dogs For Chronic Renal Failure Renal Advanced Powder is recommended for chronic renalfailure in dogs. Renal Advanced dogs can control metabolic imbalances resultingfrom chronic renal dysfunction, specially in most advanced stages. RenalAdvanced dogs can be administered in combination with Renal Powder For Dogs,depending on the evolution stage of renal dysfunction and on the consequentmetabolic conditions. Helps prevent hypokalemia with the addition of Potassium citrate Replenishes the loss of B Vitamins Helps control metabolic acidosis  Reduction of oxidative stress to kidney tissue Helps reduce azotemia Dosage and use: Easy-to-use, palatable powder is sprinkled daily onto the pet's food. Weight in Kg  Small Measures   Weight in Kg Large Measures Up to 2.5 Kg 1   10-15 Kg 2 2.5-5 Kg 2   15-25 Kg 3 5-7.5 Kg 3   25-35 Kg 4 7.5-10 Kg 4   35-50 Kg 5       Over 50 Kg 6 It is possible to split the daily dosage in 2-3administrations, according tot he number of meals. Administer Renal Advanced Dogs for 30 days, or for longer periods dependingof your veterinarian's instructions. It is preferable to mix the product with moist feed. In case of a diet based only on dry food, slightly moisten the food to ensuregood adhesion of the powder and its complete intake. Can be used either alone or in combination with theusual therapies for chronic renal failure and with specific diets for renaldysfunction, on the basis of your veterinarian's instructions. Composition: Maltodextrin, Fructooligosaccharides, Lespedeza capitata dry extract (titration4% in Rutin), Orange bioflavonoids (titration 40% in Hesperidine), Vitamin C,Enterococcus faecium SF68 (10 bln/g), Vitamin B6, Lactobacillus acidophilusDSM13241 (50 bln/g), Folic acid, Vitamin B12 Minimize