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Ion channels are membrane proteins that act as gated pathwa ... Read more

Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all cells. In recent years, an ever-increasing number of human and animal diseases have been found to result from defects in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as the channelopathies.Ion Channels and Disease provides an informative and up-to-date account of our present understanding of ion channels and the molecular basis of ion channel diseases. It includes a basic introduction to the relevant aspects of molecular biology and biophysics and a brief description of the principal methods used to study channelopathies. For each channel, the relationship between its molecular structure and its functional properties is discussed and ways in which genetic mutations produce the disease phenotype are considered. This book is intended for research workers and clinicians, as well as graduates and advanced undergraduates. The text is clear and lively and assumes little knowledge, yet it takes the reader to frontiers of what is currently known about this most exciting and medically important area of physiology. Key Features* Introduces the relevant aspects of molecular biology and biophysics* Describes the principal methods used to study channelopathies* Considers single classes of ion channels with summaries of the physiological role, subunit composition, molecular structure and chromosomal location, plus the relationship between channel structure and function* Looks at those diseases associated with defective channel structures and regulation, including mutations affecting channel function and to what extent this change in channel function can account for the clinical phenotype Minimize

Ion channels are membrane proteins that act as gated pathwa ... Read more

Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all cells. In recent years, an ever-increasing number of human and animal diseases have been found to result from defects in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as the channelopathies.Ion Channels and Disease provides an informative and up-to-date account of our present understanding of ion channels and the molecular basis of ion channel diseases. It includes a basic introduction to the relevant aspects of molecular biology and biophysics and a brief description of the principal methods used to study channelopathies. For each channel, the relationship between its molecular structure and its functional properties is discussed and ways in which genetic mutations produce the disease phenotype are considered. This book is intended for research workers and clinicians, as well as graduates and advanced undergraduates. The text is clear and lively and assumes little knowledge, yet it takes the reader to frontiers of what is currently known about this most exciting and medically important area of physiology. Key Features* Introduces the relevant aspects of molecular biology and biophysics* Describes the principal methods used to study channelopathies* Considers single classes of ion channels with summaries of the physiological role, subunit composition, molecular structure and chromosomal location, plus the relationship between channel structure and function* Looks at those diseases associated with defective channel structures and regulation, including mutations affecting channel function and to what extent this change in channel function can account for the clinical phenotype Minimize

Now in its Twelfth Edition, Diseases of Poultry continues i ... Read more

Now in its Twelfth Edition, Diseases of Poultry continues its tradition of excellence as the definitive reference of poultry disease. Following the same user-friendly format, the book has been thoroughly updated to reflect the most current knowledge of avian pathology, including new coverage of genetic resistance to disease. Coverage is given to both common and uncommon diseases, and chapters are organized by disease type, including viral, bacterial, fungal, parasitic diseases as well as others, such as nutritional, developmental, metabolic, noninfectious diseases and toxins. Each disease section provides detailed coverage of history, etiology, pathobiology, diagnosis, and intervention strategies, as well as the economic and public health significance of each disease. With a host of international authors, Diseases of Poultry is a must-have resource for all veterinary pathologists, practitioners, agricultural managers and industry leaders involved in poultry health and production. Minimize

Ageing has become a great problem for many countries. Due t ... Read more

Ageing has become a great problem for many countries. Due to world-wide life prolongation, the number of people over 60 years old has grown rapidly into a ten percent piece of the world population. The growing age of the world population raises many social, economical, and medical problems. The proportion of people in the economically active age groups to those who are over 65 is constantly decreasing. A major consequence of the increasing numbers of individuals in advanced age groups is increasing numbers of patients suffering from age-related diseases. The aim of this book is to present the basic data on human ageing as well as on age-related diseases. Minimize

Fabry disease is an X-linked inborn error of metabolism whe ... Read more

Fabry disease is an X-linked inborn error of metabolism wherein deficiency of a lysosomal enzyme results in systemic deposition of glycosphingolipids. Storage deposition, and hence pathological disease, occurs preferentially in renal glomerular and tubular epithelial cells, myocardial cells, heart valve fibrocytes, neurons of dorsal root ganglia, and in endothelial smooth muscle cells of blood vessels. Thus, Fabry disease is a multi-system disorder, albeit with considerable phenotypic heterogeneity in onset and in severity; however, it is progressive, exhibits extensive morbidity, and is life-threatening. Within the past two decades, there has been a radical change in the natural course Fabry disease by virtue of the availability of specific enzyme replacement therapy. Moreover, there has been a concerted effort to better understand the underlying pathology and equally to identify patients prior to the onset of irreversible end-organ damage. It is to be hoped that the future for patients with Fabry disease can be viewed with greater, albeit guarded, optimism. This state-of-the-art textbook attempts to bridge the span of pre-clinical studies, clinical finding, and management options in a readable but comprehensive manner for the medical practitioner as well as the interested non-medical reader. Minimize

This textbook is specifically designed for upper-division u ... Read more

This textbook is specifically designed for upper-division undergraduate or graduate students in life science or pre-medical majors including dentistry or pharmacology, who are required to take a biochemistry or medical biochemistry course, but who are not necessarily biochemistry majors. The book adopts a unique approach to the topic compared with other biochemistry textbooks currently available, in that each biochemical subject is introduced by a human disease relating the biochemical principles to be developed in that chapter. The goal is to make biochemistry more meaningful to the student who is not normally shown the connection between biochemistry and medicine. * Includes an abundance of figures* Emphasizes human biochemistry* Introduces each chapter with a relevant disease or clinical relationship Minimize

This highly anticipated color diagnostic guidebook is a tho ... Read more

This highly anticipated color diagnostic guidebook is a thorough, authoritative, and practical reference for anyone who needs to diagnose and manage disease problems in brassica crops destined for vegetable markets, seeds, oil, and condiments. Fifty-nine international disease experts contributed to the coverage of more than a dozen brassica crops: Cabbage, Cauliflower, Broccoli, Brussels Sprouts, Kohlrabi, Greens, Asian Mustard Greens, Chinese Broccoli (Chinese Kale), Chinese Cabbage, Horseradish, Radish, Turnip, Rutabaga, Oilseed Rape (Canola, Rapeseed), and Culinary or Condiment Mustards. The book covers diseases caused by fungi, bacteria, mollicutes, viruses, and nematodes, as well as noninfectious damage to brassica crops such as herbicide injury, nutrient deficiencies, postharvest disorders, genetic abnormalities, and environmental damage. Plant pathologist-reviewed color photographs provide diagnostic guidance, and current approaches to disease management are provided at the end of each section. The disease sections are preceded by a helpful introduction to the taxonomy of the various Brassica species and the genetic relationships of this extraordinarily diverse group of plant types. Brassicas are widely cultivated throughout the world as leaf or root vegetable crops, for vegetable oil production, as fodder crops for livestock feeding, or as condiments and spices. They are increasingly important economic crops, and knowledge of their diseases is critical as is evidenced by the disease problems associated with the large increase in global production of both vegetable and oilseed brassicas. This compendium will be essential for extension scientists working in agriculture and horticulture and for other advisors, including individuals in regulatory agencies, as well as those in the private sector dealing with seed and fungicide retail and with disease scouting. The book is also useful for brassica crop growers, plant pathology and agriculture science teachers, students, research scientists, and plant breeders. This book comes in the new and improved APS PRESS Compendia Series format with color throughout and images included in the disease section. Minimize

This comprehensive book examines how mineral nutrition affe ... Read more

This comprehensive book examines how mineral nutrition affects plant disease. Minerals improve the overall quality and health of plants. Knowing how each individual mineral affects a plant is beneficial for efficiency in production and sustaining the ecosystem. From a plant pathology perspective, Mineral Nutrition and Plant Disease brings the discussion of plant disease diagnosis and management to a new level. Mineral nutrients are important in production agriculture and horticulture because they can often be the first line of defense against plant diseases. It is an area of knowledge that can be misunderstood or overlooked in the study of diseases and their diagnosis. This reference succeeds in organizing what we know and explaining the interactions at work. Mineral Nutrition and Plant Disease is the first book to successfully combine two important plant science disciplines, nutrition and pathology, to provide current information on theoretical aspects of nutrition in disease physiology while contributing a wealth of basic practical information for obtaining immediate disease suppression with specific fertilizers.Special Features: Provides a holistic overview of how minerals are made available in soil and their basic function in plants Helps you understand the interacting affects of minerals on all types of diseases Abiotic as well as biotic Identifies mineral nutrient forms, physiological functions, and interactions with numerous diseases Provides valuable tables showing nutrient-disease interactions that facilitate the use of nutrients to manage diseases Tabulates extensive literature reviews with tables to help you perform quick searches for any host/disease systemThe book is peer-reviewed and multi-authored by scientists with expertise relating to each specific mineral element. A user-friendly benefit of this book is that each chapter focuses on one specific mineral element and explains the relationship between the nutrient and its affect on plant diseases. Each chapter describes the critical levels of each element involved in plant disease interactions, the effects of these elements on pathogens and plants, and the known mechanisms of how these elements suppress plant diseases. Benefits of specific mineral nutrients in each chapter recognize their interdependent interaction with each other and all aspects of the plant physiology, genetics, and the environment. These mineral nutrient chapters are preceded by two helpful chapters on the Chemistry of Plant Nutrients in Soil and The Physiological Role of Minerals in the Plant. The purpose of this important treatise is to outline the current knowledge of mineral nutrition and plant diseases. Readers will gain practical information for immediate disease management and understand the physiological role of each element in the plant and how it contributes to disease. Editors Datnoff, Elmer, and Huber, have done a commendable job in collaboration with their expert contributors. This book is pertinent to plant scientists worldwide including agronomists, plant physiologists, horticulturists, extension scientists, soil scientists, plant pathologists, and librarians who serve them. It will also be useful as a fundamental text to use for introductory courses in these disciplines. Minimize

Compendium of Soybean Diseases, 4th Edition combines the fi ... Read more

Compendium of Soybean Diseases, 4th Edition combines the finest qualities of best-selling previous editions with updated and new sections, making it a thorough, authoritative and practical reference. Revisions to the 4th Edition include five new sections on different leaf spot diseases, an updated section on sudden death syndrome and many new color photographs. Soybean growers and crop advisors worldwide will find this color guidebook indispensable for preventing, diagnosing and controlling more than 100 diseases and disorders of soybean.Table of ContentsPreface; Introduction; Soybean Origin, Germ Plasm, Growth, Production, and Utilization; Soybean Diseases; Part 1: Infectious Diseases; Diseases Caused by Prokaryotes; Bacterial Diseases; Blight; Pustule; Tan Spot; Wildfire; Bacterial Wilts; Seedborne Bacteria; Other Bacteria; Crown Gall; Noneffective Biological Nitrogen Fixation; Diseases Associated with Mollicutes; Bud Proliferation; Machismo; Phyllody and Witches'-Broom; Update of Phytoplasmas in North America; Diseases Caused by Fungi; Fungal Diseases of Foliage, Upper Stems, Pods, and Seeds; Alternaria Leaf Spot and Pod Necrosis; Anthracnose; Aristostoma Leaf Spot and Yellowing; Black Leaf Blight; Brown Spot; Cercospora Blight, Leaf Spot, and Purple Seed Stain; Choanephora Leaf Blight; Downy Mildew; Drechslera Leaf Blight; Frogeye Leaf Spot; Leptosphaerulina Leaf Spot; Phyllosticta Leaf Spot; Powdery Mildew; Red Leaf Blotch; Rhizoctonia Foliar Blight; Rust; Scab; Stemphylium Leaf Spot; Target Spot; Fungal Diseases of Lower Stems and Roots; Brown Stem Rot; Charcoal Rot; Diaporthe-Phomopsis Complex; Phomopsis Seed Decay; Pod and Stem Blight; Stem Canker; Fusarium Diseases; Fusarium Blight or Wilt, Root Rot, and Pod and Collar Rot; Fusarium spp. Associated with Seeds; Sudden Death Syndrom; Phytophthora Rot; Pythium Damping-Off and Root Rot; Red Crown Rot; Rhizoctonia Root Rot; Sclerotinia Stem Rot; Sclerotium Blight; Thielaviopsis Root Rot; Other Fungi Associated with Root Rots; Other Fungi Reported in Soybean; Diseases Caused by Nematodes; Soybean Cyst; Lance; Lesion Reniform; Root Knot; Sting; Other Nematodes; Diseases Caused by Viruses; RNA; Alfamovirus; Alfalfa mosaic; Bromovirus; Cowpea Chlorotic Mottle; Carlavirus; Cowpea Mild Mottle; Carmovirus; Black Gram Mottle; Comoviruses Bean Pod Mottle; Cowpea Severe Mosaic; Other Comoviruses; Cucumoviruses; Soybean and Peanut Stunt; Furovirus; Soybean Yellow Vein; Ilarvirus; Tobacco Streak; Leteoviruses; Indonesian Soybean Dwarf; Soybean Dwarf; Nepoviruses; Soybean Severe Stunt; Tobacco Ringspot; Other Nepoviruses Potyviruses; Bean Yellow Mosaic; Peanut Mottle; Soybean Mosaic; Tobamovirus; Tobacco Mosaic; DNA; Begomoviruses; Mungbean Yellow Mosaic; Soybean African Dwarf; Soybean; Crinkle Leaf; Caulimovirus; Soybean Chlorotic Mottle; Genome Unknown; Soybean Mild Mosaic; Other Virus Diseases; Seed and Postharvest Pathology; Detection of Seedborne Pathogens; Seedborne Bacteria; Seedborne Field Fungi; Yeast Spot; Other Seedborne Field Fungi; Storage Fungi;Part 2: Noninfectious or Stress Disorders Crusting and Compaction; Frost; Hail; Heat Canker; Lightning; Sunburn; Water Stress; Mineral Deficiencies and Toxicities; Herbicide Damage; Insecticide Damage; Air Pollutants;Part 3: Soybean Disease Management Strategies Introduction; Preventive Measures; Preemptive Measures; Remedial Measures; Appendix; Index Minimize

Increased oxidative stress due to the production of excessi ... Read more

Increased oxidative stress due to the production of excessive amounts of free radicals along with the effects of chronic inflammation play a major role in the initiation and progression of a host of disease states, ranging from cancer to posttraumatic stress disorder. In varying doses, micronutrients, including antioxidants, B vitamins, and minerals have shown to help ameliorate these effects. However, clinical studies using isolated micronutrients to combat these illnesses have proven that such limited therapy has produced inconsistent results. Assembling a plethora of rational and scientific evidence, Micronutrients in Health and Disease makes the case that the use of not one but multiple micronutrients working together synergistically in combination with a low-fat, high-fiber diet can prove successful in the prevention and management of these chronic conditions. Following an overview of basic facts about micronutrients, oxidative stress, inflammation, the immune system, and the results of various clinical studies, the book explores the use of micronutrients in prevention and improvement of standard therapy in a number of disease states, including: Coronary artery disease Diabetes Cancer Alzheimer’s disease Parkinson’s disease Hearing disorders Posttraumatic stress disorder Traumatic brain injury HIV/AIDS Adverse effects of radiation Arthritis Steeped in research and heavily referenced, this volume concludes with a list of common myths and misconceptions about micronutrient use and a chart with dietary reference intakes (DRIs) of all the major products, making this a solid resource for those seeking to promote healthy aging and prevent and manage disease. Minimize

Liberally illustrated throughout with over 400 photographs ... Read more

Liberally illustrated throughout with over 400 photographs (300 in full colour), this reference provides a practical and clinically oriented approach to the diagnosis and management of macular disorders. It covers not only diseases that primarily affect the macula, such as age-related macular degeneration, but also those that might have an indirect but never-the-less significant effect on macular function, such as vascular and inflammatory diseases. Many diseases in this book are illustrated with brief case studies, to help bring them to life and facilitate learning.With over 400 top quality clinical pictures, this book enables easy visual recognition of macular diseases. Covers all disorders associated with macular degeneration not only age-related macular degeneration. Includes case histories which is an invaluable and unique diagnostic tool that facilitates learning. Each chapter covers the most common disease first, followed by less common conditions which guides the reader towards an accurate diagnosis. Written as a quick and easy reference. Minimize

This healing ointment can be used for a wide range of skin ... Read more

This healing ointment can be used for a wide range of skin problems. It is mildly drawing and cleansing to the skin or to any superficial injuries. May be used on cuts, burns, sunburn, bruises, boils, herpes, skin diseases, cancer, insect bites, bee stings, rashes, psoriasis, eczema, hemorrhoids, poison ivy, inflammations, varicose veins, and swellings. Covering the affected area may help promote absorption of the ointment and keep the area clean, but it can be applied uncovered. Cautions: Do not exceed recommended dosage. Avoid concomitant use with other herbs or supplements unless under the supervision of a health care practitioner. Note: This ointment may stain the clothes. Consult a health care practitioner before using with prescription or other medication and before using with pre-existing medical or acute conditions or disease (including diarrhea). Avoid exposure to sunlight or artificial light sources emitting UVA. Consult a health care practitioner if symptoms persist. May increase liver function tests, lower blood glucose test results, or increase bilirubin test results Discontinue use if you experience local irritation and inflammation, allergic contact eczema, allergic contact dermatitis, skin dryness, pruritus, stinging, burning, or redness. Do not use if pregnant or breastfeeding, if there is skin damage over a large area, or topically in children under 2 years of age. Minimize

This healing ointment can be used for a wide range of skin ... Read more

This healing ointment can be used for a wide range of skin problems. It is mildly drawing and cleansing to the skin or to any superficial injuries. May be used on cuts, burns, sunburn, bruises, boils, herpes, skin diseases, cancer, insect bites, bee stings, rashes, psoriasis, eczema, hemorrhoids, poison ivy, inflammations, varicose veins, and swellings. Covering the affected area may help promote absorption of the ointment and keep the area clean, but it can be applied uncovered. Cautions: Do not exceed recommended dosage. Avoid concomitant use with other herbs or supplements unless under the supervision of a health care practitioner. Note: This ointment may stain the clothes. Consult a health care practitioner before using with prescription or other medication and before using with pre-existing medical or acute conditions or disease (including diarrhea). Avoid exposure to sunlight or artificial light sources emitting UVA. Consult a health care practitioner if symptoms persist. May increase liver function tests, lower blood glucose test results, or increase bilirubin test results Discontinue use if you experience local irritation and inflammation, allergic contact eczema, allergic contact dermatitis, skin dryness, pruritus, stinging, burning, or redness. Do not use if pregnant or breastfeeding, if there is skin damage over a large area, or topically in children under 2 years of age. Minimize

Recent interest in new diseases, such as HIV/AIDS and Ebola ... Read more

Recent interest in new diseases, such as HIV/AIDS and Ebola, and the resurgence of older diseases like tuberculosis has fostered questions about the history of human infectious diseases. How did they evolve? Where did they originate? What natural factors have stalled the progression of diseases or made them possible? How does a microorganism become a pathogen? How have infectious diseases changed through time? What can we do to control their occurrence? Ethne Barnes offers answers to these questions, using information from history and medicine as well as from anthropology. She focuses on changes in the patterns of human behavior through cultural evolution and how they have affected the development of human diseases. Writing in a clear, lively style, Barnes offers general overviews of every variety of disease and their carriers, from insects and worms through rodent vectors to household pets and farm animals. She devotes whole chapters to major infectious diseases such as leprosy, syphilis, smallpox, and influenza. Other chapters concentrate on categories of diseases ("gut bugs," for example, including cholera, typhus, and salmonella). The final chapters cover diseases that have made headlines in recent years, among them mad cow disease, West Nile virus, and Lyme disease. In the tradition of Berton Roueché, Hans Zinsser, and Sherwin Nuland, Ethne Barnes answers questions you never knew you had about the germs that have threatened us throughout human history. Minimize

This monograph presents the knowledge of tongue examination ... Read more

This monograph presents the knowledge of tongue examination of warm diseases of Traditional Chinese Medicine (TCM) with pictures and accompanying essays. There are more than 150 pictures and essays in this book, which gives a brief summary of characteristics, indications and treatment principles of the tongues appearance in warm diseases. Based on the national textbook, Seasonal Febrile Disease of TCMWn Bìng Xué, this book is recommended for educational purposes. As an important diagnostic method in epidemic febrile disease, tongue examination has been highly valued by doctors through the ages. Today the skillful and correct mastery of it is a basic requirement for modern physicians in clinical practice. All the pictures of the tongue were taken from patients suffering from warm disease including acute epidemic disease, acute infectious disease, and burns. Pictures in this book cover lips, tooth, and even the face, including an oily and dirty face, flushed face, gum bleeding, mouth corner bleeding, dry lip, and lip sores, in order to clarify the relationships between tongue and other manifestations. The tongue manifestations in this book are classified and edited according to the national textbook, Seasonal Febrile Disease of TCM (Wn Bìng Xué, ), and the systematic and broad scope of the content is beneficial for teaching. All the pictures in this book come from clinics. Some pictures, like those of tongue sores, linguofacial blood-streak, and sublingual varicosity, are rare and unique and can be used to supplement textbooks. This book is mainly consists of pictures of the tongue, with brief introductions covering the characteristics, indications and treatment principles of tongue manifestations in warm disease. It is a good clinical reference for doctors. Finally, any corrections and/or suggestions concerning its content would be appreciated. Minimize

First published in 1983, Diseases of Sheep has become a def ... Read more

First published in 1983, Diseases of Sheep has become a definitive reference book on sheep diseases. This new edition has been revised and updated to maintain its original core structure and its international approach to the many diseases which affect sheep. Any veterinary surgeon or agriculturalist who works with sheep will continue to find the information in this book the most authoritative and comprehensive available. Known to many as the "Moredun Sheep Book" because of its association with the Moredun Research Institute, long recognised as a centre of excellence in sheep disease research. Special attention is given to specific regional disease problems in the Middle East, Southern Africa, Australia, New Zealand, North America and South America. Covers technical aspects of disease prevention and treatment, including uncommon diseases, as well as sheep welfare issues. Minimize

Learn about the benefits of transitioning to a healthier di ... Read more

Learn about the benefits of transitioning to a healthier diet in order to fight diseases such as fibromyalgia, lupus, chronic fatigue, migraine headaches, and other inflammatory based conditions; or learn how to eat well just to stay healthy in general. This book is a guide to fighting inflammatory diseases, fibromyalgia, chronic fatigue syndrome, polymyalgia, lupus and other autoimmune based disorders. In this book Dr. Clairborne explores what foods cause inflammation, why preparation method is so important, and how to use the anti-inflammatory diet to change the course of any inflammatory disease. She gives a summary of healthy detoxification and supplements that she considers essential to cleansing and to every day health and well-being. She then takes the reader on a journey through the processes of healthy shopping, meal planning, healthy cooking basics, and quick preparation for the busy person. Finally she will share simple, fun, and practical tips that the reader can incorporate into an efficient daily practice through meal planning. By the end of this book the reader will understand the body's inflammatory process, know how to use food to reverse this, and realize that it doesn't have to be overwhelming, stressful, or expensive, and that it can in fact be quite simple, tasty, cost effective and even fun. Minimize

Pancreatic Disease: Basic Science and Clinical Management s ... Read more

Pancreatic Disease: Basic Science and Clinical Management summarises the state of the art in basic science and clinical management of pancreatic disease. This book provides a clear and up-to-date review of the advancing areas in clinical pancreatology and clinical research related to the pancreas. Written by leading experts in the field, this comprehensive review directs the interested reader towards important and current published source material. Covering all aspects of pancreatic disease, contributions are included from pancreatic surgeons and medical pancreatologists on pancreatic cancer, acute pancreatitis and chronic pancreatitis. Special features include a systematic review of the evidence for the use of gemcitabine in pancreatic cancer prepared for the National Institute of Clinical Excellence (NICE), the UK body charged with evaluating new drug treatment. Gemcitabine has FDA approval. There are several contributions dealing with the management of pancreatic neuroendocrine tumours. This book will be useful to gastroenterologists, internists and surgeons, and specialist clinicians with an interest in pancreatic disease. Trainees in medical and surgical pancreatology will find it a companion to supplement standard textbooks. Minimize

Staphylococci remain the most important cause of hospital-a ... Read more

Staphylococci remain the most important cause of hospital-acquired infections in the U.S. and MRSA has become the most common cause of skin and soft tissue infection in many parts of the world.There is now a much greater understanding of the physiology and evolution of the staphylococci and this new edition reflects the rapid advancements in knowledge about this pathogen and provides a comprehensive review from both clinical and basic science perspectives.The first section addresses the basic biology of the staphylococci, their molecular genetics, host defenses and host evasion, virulence determinants, mechanisms of antibiotic resistance, and laboratory techniques. The second section deals with epidemiology, and the third section provides an overview of the varied clinical manifestations of human staphylococcal infections. The fourth section covers prevention and treatment of these often life-threatening infections.Written by experts from around the globe, this book is essential reading for all clinicians and basic scientists studying the staphylococci. Minimize

Whether they are called peppers, chiles, paprika, or ajis, ... Read more

Whether they are called peppers, chiles, paprika, or ajis, plants in the genus Capsicum, are among the most important spice and vegetable commodities worldwide because they are used in so many different types of food. Like other crops, peppers are afflicted with diseases, disorders, and pests that can reduce fruit quality and yield.The Compendium of Pepper Diseases provides a comprehensive presentation of the important pepper diseases of the world. With the help of 122 color photographs and thorough descriptions of pathogens, this valuable reference enables readers to easily identify diseases on the basis of symptoms and formulate field and laboratory diagnoses of diseases caused by bacteria, fungi, viruses, parasitic angiosperms, and nematodes.Readers will also learn about the geographical distribution and impact of each disease, control measures, and epidemiological aspects of diseases as well as gain knowledge on plant health problems associated with arthropods, nutritional deficiencies, herbicide injuries, and other abiotic causes. This compendium also includes sections discussing the botany of pepper, current production practices, and postharvest damage to pepper fruit.Edited and authored by 39 professionals with international expertise in pepper pathology in several unique production areas and in diverse areas of pathogen expertise, the Compendium of Pepper Diseases will prove invaluable to growers, extension agents, county agents, crop production specialists, researchers, plant pathologists, horticulturists, agronomists, agribusiness professionals, educators, students and anyone interested in the diagnosis or management of diseases of pepper crops throughout the world. Minimize

Now in its Twelfth Edition, Diseases of Poultry continues i ... Read more

Now in its Twelfth Edition, Diseases of Poultry continues its tradition of excellence as the definitive reference of poultry disease. Following the same user-friendly format, the book has been thoroughly updated to reflect the most current knowledge of avian pathology, including new coverage of genetic resistance to disease. Coverage is given to both common and uncommon diseases, and chapters are organized by disease type, including viral, bacterial, fungal, parasitic diseases as well as others, such as nutritional, developmental, metabolic, noninfectious diseases and toxins. Each disease section provides detailed coverage of history, etiology, pathobiology, diagnosis, and intervention strategies, as well as the economic and public health significance of each disease. With a host of international authors, Diseases of Poultry is a must-have resource for all veterinary pathologists, practitioners, agricultural managers and industry leaders involved in poultry health and production. Minimize

The authority of Harrison's in a handy, full-color paperbac ... Read more

The authority of Harrison's in a handy, full-color paperback devoted exclusively to Infectious Diseases 5 STAR DOODY'S REVIEW! "This book provides all the latest knowledge in the field and is supported by the scientific rigor and reliability that have defined Harrison's....This book is an essential compact clinical companion for students and clinicians alike....This book is complete, easy to navigate, and remarkably up to date. As the parent text does, this book devotes significant attention to the importance of obtaining a history and conducting a physical examination, the basic foundation of all medicine. It blends the other myriad aspects of infectious diseases and offers eminently readable and current management recommendations. Indeed, it should be regarded as an authoritative source of current information on infectious diseases."--Doody's Review Service Featuring the chapters on Infectious Diseases that appear in the landmark Harrison's Principles of Internal Medicine, 17e, this compact clinical companion delivers all the latest knowledge in the field, backed by the scientific rigor and reliability that have defined Harrison's. You'll find coverage that reflects the expertise of renowned editors and contributors -- presented in a carry-anywhere format that makes it ideal for the classroom, the wards, or the point of care. With its ease of use, indispensable diagnosis-speeding guidelines, and acclaimed state-of-the-art strategies, Harrison's Infectious Diseases is a must for students and clinicians alike. Harrison's Infectious Diseases delivers: Current, complete coverage of essential infectious diseases topics, including infections in organ systems, bacterial infections, viral infections, prion diseases, fungal and algal infections, and protozoal and helminthic infections 100+ high-yield Q&A drawn from Harrison's Principles of Internal Medicine Self-Assessment and Board Review, 17e 6 complete chapters in print format from the Harrison's DVD 127 chapters written by experts who have made significant contributions to knowledge in their fields References and other material that have been updated since the publication of HPIM 17e Integration of pathophysiology with clinical management topics in each of the disease-oriented chapters Helpful appendix of laboratory values of clinical importance The Harrison’s specialty series is written by the same world-renowned author team who brought you Harrison’s Principles of Internal Medicine, 17e: Anthony S. Fauci, MD; Eugene Braunwald, MD; Dennis L. Kasper, MD; Stephen L. Hauser, MD; Dan L. Longo, MD; J. Larry Jameson, MD, PhD; Joseph Loscalzo, MD, PhD Minimize

The fully revised second edition of the Encyclopedia of Hea ... Read more

The fully revised second edition of the Encyclopedia of Heart Diseases is an ideal resource for practicing clinicians and researchers. Available in print, online, and with dual access, it is a clear and comprehensive aggregation of the most crucial information and essential data on cardiovascular diseases and therapeutics. Comprised of over 95 entries with regular online updates, the Encyclopedia of Heart Diseases is fully referenced, and major points of interests are hyperlinked to complementary sections. Each entry is logically and superbly written, providing accurate core knowledge of pathogenesis, pathophysiology, clinical features, diagnostic techniques, and management strategies. Specific detail is paid to technological advances in imaging and diagnostics. Therapy focused entries give powerful insights into not only prescribing drug regimens, but also into the controversies surrounding their use. This major reference work is invaluable for all those involved in the care of cardiovascular patients. From the front-line practitioner to the basic science researcher to the student in training, the Encyclopedia of Heart Diseases offers an astute authoritative guide to navigating an immense body of fascinating information. From the trainee to the internist and cardiologist, all will find it useful. It is an essential resource for medical libraries and academic institutions worldwide.   From the Foreword: So, what would we want from an encyclopedia on heart disease? Ideally, a book would be comprehensive, yet concise, and be practically oriented, and explain pathophysiology and treatment. In addition, it should be accessible online so that it can be accessed at the bedside or anywhere. Dr. Khan has written exactly such a book. Encyclopedia of Heart Diseases is comprehensive, yet concise, and very practically oriented. Importantly, it takes a step-by-step approach, walking the reader through a thorough pathophysiology of conditions, their evaluation and treatment. For therapies, he provides the mechanism of the drug, its doses, side effects and clinical efficacy. ...A terrific online resource with all the information you need! - Christopher P. Cannon, MD, TIMI Study Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA Minimize

Disease-related malnutrition is a global public health prob ... Read more

Disease-related malnutrition is a global public health problem. The consequences of disease-related malnutrition are numerous, and include shorter survival rates, lower functional capacity,longer hospital stays, greater complication rates, and higher prescription rates.Nutritional support, in the form of oral nutritional supplements or tube feeding, has proven to lead to an improvement in patient outcome. This book is unique in that it draws together the results of numerous different studies that demonstrate the benefits of nutritional support and provides an evidence base for it. It also discusses the causes, consequences, and prevalence of disease-related malnutrition, and provides insights into the best possible use of enteral nutritional support. Minimize

Learn about the benefits of transitioning to a healthier di ... Read more

Learn about the benefits of transitioning to a healthier diet in order to fight diseases such as fibromyalgia, lupus, chronic fatigue, migraine headaches, and other inflammatory based conditions; or learn how to eat well just to stay healthy in general. This book is a guide to fighting inflammatory diseases, fibromyalgia, chronic fatigue syndrome, polymyalgia, lupus and other autoimmune based disorders. In this book Dr. Clairborne explores what foods cause inflammation, why preparation method is so important, and how to use the anti-inflammatory diet to change the course of any inflammatory disease. She gives a summary of healthy detoxification and supplements that she considers essential to cleansing and to every day health and well-being. She then takes the reader on a journey through the processes of healthy shopping, meal planning, healthy cooking basics, and quick preparation for the busy person. Finally she will share simple, fun, and practical tips that the reader can incorporate into an efficient daily practice through meal planning. By the end of this book the reader will understand the body's inflammatory process, know how to use food to reverse this, and realize that it doesn't have to be overwhelming, stressful, or expensive, and that it can in fact be quite simple, tasty, cost effective and even fun. Minimize

The neck dissection has evolved over time by defining its a ... Read more

The neck dissection has evolved over time by defining its applications, tailoring it to the extent and location of regional disease, thereby using this information to expand or reduce the magnitude of the surgery itself. It has been labeled radical, functional, modified and selective depending on the sacrifice or preservation of certain muscles, nerves or vessels. The aim, however, has always been to encompass the lymph nodes at risk of harboring cancer. It has been described as elective (N0) or therapeutic (N+). It has been declared useful and appropriate for treating the neck in conjunction with cancers arising in the thyroid, the skin, the salivary glands, and the mucosa of the upper aerodigestive tract. In Neck Dissection: Management of Regional Disease in Head and Neck Cancer, Drs. Ferlito, Robbins and Silver have done a masterful job in compiling the collective wisdom of the best minds in the discipline; past and present. The information contained in the various chapters enlightens, inspires and challenges us. This book addresses the subject of node metastasis, its diagnosis, pathology, treatment and outcomes. Nothing is more important to the head and neck surgeon than to have a basic understanding of, and a "hands-on" familiarity with the various surgical options for treatment of cancer in the neck. The authors make it perfectly clear however, that it is still a work in progress. This progress comes with a price. Surgeons today are confronted with many choices or options regarding management of the neck in any particular case. No longer is only one type of dissection to be applied to all circumstances. In addition, many of these new choices are more tedious and technically challenging than the standard radical neck dissection. A poorly performed selective or modified neck dissection can result in an inadequate number or an inappropriate level of nodes removed, thus defeating its purpose. Minimize

Everything you need to know about neuromuscular disease--in ... Read more

Everything you need to know about neuromuscular disease--in one concise, full-color volume "...this book will become an indispensable resource for clinicians involved in the diagnosis and management of patients with neuromuscular diseases, as well as for scientists working on the nature and pathogenesis of these disorders. It is a much-needed and welcome addition to the neurological literature and will rapidly gain acceptance as a standard work of reference."--Michael J. Aminoff, MD, DSc, FRCP, (from the foreword) Neuromuscular Disorders is comprehensive in scope, yet concise enough to serve as a valuable point-of-care guide for your day-to-day clinical practice. Grounded by numerous reference sources and enhanced by the experience of two seasoned clinicians, this text provides a pragmatic approach to the evaluation and management of neuromuscular disease. Here, in a single source, you'll get an insightful look at both nerve and muscle conditions, ranging from motor neuron diseases to neuropathies, neuromuscular junction disorders, and myopathies. The book opens with the clinical and laboratory approach to patients with neuromuscular disease, covering electrodiagnostic testing, nerve conduction studies, and muscle and nerve histopathology. With an emphasis on effective diagnosis and treatment, the substance of the text examines the full spectrum of specific neuromuscular diseases, giving you the “big picture” of the discipline in a way that no other text can match. FEATURES: Convenient coverage of both nerve, muscle and neuromuscular transmission disorders--both primary and secondary neuromuscular diseases Specific disease sections encompass the range of conditions likely to be encountered in clinical practice, including amyotrophic lateral sclerosis, myasthenia gravis, radiculopathies and plexopathies, mononeuropathies, various polyneuropathies, toxic myopathies, and dozens more The very latest diagnosis and treatment recommendations and protocols based on the most recent clinical literature and research Well-illustrated with EMGs, histopathology, and clinical photos Minimize

Plant disease epidemics, caused by established and invasive ... Read more

Plant disease epidemics, caused by established and invasive pathogen species, continue to impact a world increasingly concerned with the quantity and quality of its primary food supply. The Study of Plant Disease Epidemics is a comprehensive manual that introduces readers to the essential principles and concepts of plant disease epidemiology. This useful reference and textbook provides a detailed exposition on how to describe, compare, analyze, and predict epidemics of plant disease for the ultimate purposes of developing and testing control strategies and tactics. The authors have synthesized the research advances from the last four decades, with a special emphasis on research done in the last 15 years, to produce a useful framework for: - Measuring plant disease - Quantifying and modeling disease development in time and space - Quantifying patterns of disease and sampling for disease in populations - Determining decision thresholds for control interventions - Characterizing the relationship between disease development and crop loss This new reference introduces a coherent theory of disease development in plant host populations over time and space, coupled with detailed explanations of the components of diseases in crops and forests. This theory demonstrates how different levels of mathematical complexity can lead to unifying principles of disease invasion, persistence, and rates of temporal increase and disease expansion from foci. In addition, the book shows how disease control strategies are intricately related to fundamental population-biology parameters. The information on modeling and statistical analysis provides the needed tools and procedures for researchers to help them properly measure and analyze collected epidemiological data and maximize its value. The methods and principles described throughout the book explain how to translate this valuable data and utilize it to make informed disease management decisions.The Study of Plant Disease Epidemics is the highly anticipated original work by three of the leading plant disease epidemiologists of the last quarter century. This manual is an essential tool intended for graduate students, researchers, and teachers of plant pathology, as well as crop consultants and those in disease management positions. It will be an excellent teaching tool for courses in Plant Disease Epidemiology, Plant Disease Management, Invasive Species Risk Assessment, and Plant Pathogen Ecology. Minimize

In the 1850s, "Drapetomania" was the medical term for a dis ... Read more

In the 1850s, "Drapetomania" was the medical term for a disease found among black slaves in the United States. The main symptom was a strange desire to run away from their masters. In earlier centuries gout was understood as a metabolic disease of the affluent, so much so that it became a badge of uppercrust honor -- and a medical excuse to avoid hard work. Today, is there such a thing as mental illness, or is mental illness just a myth? Is Alzheimer's really a disease? What is menopause -- a biological or a social construction?Historically one can see that health, disease, and illness are concepts that have been ever fluid. Modern science, sociology, philosophy, even society -- among other factors -- constantly have these issues under microscopes, learning more, defining and redefining ever more exactly. Yet often that scrutiny, instead of leading toward hard answers, only leads to more questions. Health, Disease, and Illness brings together a sterling list of classic and contemporary thinkers to examine the history, state, and future of ever-changing "concepts" in medicine. Divided into four parts -- Historical Discussions; Characterizing Health, Disease, and Illness; Clinical Applications of Health and Disease; and Normalcy, Genetic Disease, and Enhancement: The Future of the Concepts of Health and Disease -- the reader can see the evolutionary arc of medical concepts from the Greek physician Galen of Pergamum (ca. 150 ce) who proposed that "the best doctor is also a philosopher," to contemporary discussions of the genome and morality. The editors have recognized a crucial need for a deeper integration of medicine and philosophy with each other, particularly in an age of dynamically changing medical science -- and what it means, medically, philosophically, to be human. Minimize